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Medication Doses

The following doses are for guidance only; the user is responsible for ensuring accuracy of the information below and should follow manufacturer recommendations for all doses.
Medication Dosing Guidelines
Ethanol
  • Maximum dose: 1 ml/kg
  • Typical dose: approximately 0.5 ml/kg
  • Total volume: not exceeding 60 ml per procedure
  • Important: Avoid tourniquets - sudden discharge into circulation can cause cardiovascular collapse
Sodium Tetradecyl Sulfate 3%
  • Maximum dose: 0.5 ml/kg
  • Total volume: not exceeding 30 ml per procedure
  • Preparation: Reconstituted into foam with water soluble contrast or lipiodol (more stable foam) and air
Bleomycin
  • Maximum dose: 1 unit/kg
  • Typical dose: closer to 0.5 units/kg (especially in infants and small children)
  • Total dose: not to exceed 15 units per session
  • Preparation: Reconstituted in pharmacy at 2 units/ml, dilute with equal volume of water-soluble contrast for final concentration of 1 unit/ml
Doxycycline
  • Maximum dose: 20 mg/kg
  • Total dose: not to exceed 1000 mg per session
  • Preparation: Reconstituted with saline to 20 mg/ml, dilute with equal volume of water-soluble contrast for final concentration of 10mg/ml
  • Caution: If using near maximum dose in neonates/infants, monitor for hypoglycemia
Local Anesthetics
  • Lidocaine 1%: 0.5 ml/kg
  • Bupivacaine 0.25%: 1 ml/kg
Heparin
  • Angiography (children < 10 kg): Consider prophylactic dose of 50 U/Kg after sheath placement to avoid access site thrombosis
  • Loading dose: 100 U/Kg just prior to angioplasty
  • Maintenance: Maintain ACT at 200-250, can re-dose every 60-90 minutes if necessary
  • CDT: See thrombolysis guidelines
Alteplase
  • Catheter Directed Thrombolysis: See CDT guidelines
  • Acute vascular loading dose: 0.1–0.3 mg/kg over 10–30 min, maximum of 2 mg
  • Chest tube: 4 mg if >20kg, 0.2 mg/kg if <20kg. Dwell time 2 hours
Enoxaparin (Lovenox)
  • Prophylactic: 0.5 mg/kg Q 12 hours
  • Therapeutic: 1 mg/kg Q 12 hours
Analgesics
  • Acetaminophen: 15 mg/kg PO/PR q4 h PRN
  • Ibuprofen: 10 mg/kg/dose q6–8h PRN
Aspirin
  • Post-angioplasty: Depending on age, half or full (81 mg) baby aspirin for 1 month
  • Venous malformations: Some patients find it helpful with pain due to thrombi; half or full (81 mg) baby aspirin depending on size
Nitroglycerin
  • Dose: 1 microgram/kg
Glucagon
  • Dose: 10 mcg/Kg, maximum 1 mg
Dexamethasone
  • Post-sclerotherapy/embolization: IV 0.1-0.5 mg/kg Q 8 hr
  • Maximum dose: 8-12 mg

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  • Home
  • Procedures
  • Protocols
  • Online Library
    • Pediatric IR Papers
    • Presentations and Webinars
    • IR Equipment and IFU
  • BCH IR Fellows Homepage
  • About Us